When should the test be performed?
BACTEC MGIT 960 PZA is a qualitative method for assessing the susceptibility of Mycobacterium tuberculosis to pyrazinamide (PZA), one of the key first-line anti-tuberculosis drugs. Indications for performing the test include:

  • Confirmed tuberculosis infection
  • Monitoring the effectiveness of anti-TB therapy
  • Diagnosis of multidrug-resistant tuberculosis (MDR-TB)
  • Verifying PZA susceptibility in cases of resistance to other first-line drugs
  • Epidemiological studies on M. tuberculosis drug resistance

Test description
The test uses the BACTEC MGIT 960 system to rapidly and accurately assess the growth of mycobacteria in the presence of a critical concentration of pyrazinamide.

  • The method is based on detecting M. tuberculosis growth in MGIT (Mycobacteria Growth Indicator Tube) liquid medium under acidic pH conditions
  • The system automatically records results and analyzes drug susceptibility
  • It provides accurate results in a shorter time compared to classical phenotypic methods
  • Automated growth detection eliminates subjective interpretation, increasing the reliability of the test