Tuberculosis
When should the test be performed?
GeneXpert MTB/XDR is an advanced, automated diagnostic method based on PCR technology, enabling the rapid detection of Mycobacterium tuberculosis and its resistance to key drugs used in the treatment of multidrug-resistant (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB). Indications for the test include:
- Suspected MDR-TB or XDR-TB
- Tuberculosis diagnosis in patients with treatment failure
- Verification of drug resistance in patients with confirmed TB
- Monitoring the effectiveness of anti-TB therapy
- TB diagnostics in populations at high risk of drug-resistant strain infection
Test description
GeneXpert MTB/XDR is one of the fastest methods for identifying tuberculosis and assessing its resistance to critical second-line drugs. The system detects M. tuberculosis genetic material and mutations associated with resistance to:
- Isoniazid
- Fluoroquinolones
- Amikacin
- Kanamycin
- Capreomycin
- Ethionamide
The analysis is performed on sputum and other clinical specimens. The fully automated system eliminates the need for multi-step laboratory processing, minimizing the risk of contamination. Results are available within a few hours, allowing for rapid initiation of appropriate therapy.